Anti-Human EGFR Rabbit Recombinant Antibody proteintech 98344-1-RR
$145.00
In stock
SKU
98344-1-RR
242684A1, EGF R, EGF Receptor , Epidermal growth factor receptor, Proto-oncogene c-ErbB-1
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) |
| Applications: FC | Observed Molecular Weight: NM_005228.5 |
| Formulation: PBS, Azide | GenBank Accession Number: 1956 |
| Conjugate: Unconjugated | Gene Symbol: Unconjugated |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Liquid |
| Application: Flow Cytometry (FC) | RRID: Protein A purification |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: P00533 |
| Tested Reactivity: Human | Form: PBS with 0.09% sodium azide, pH 7.3. |
| Host / Isotype: Recombinant | Background Information: EGFR, also named as ERBB1, is a cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. The gene resides on chromosome 7p12, encoding a 170 kDa membrane-associated glycoprotein. Recent studies have shown EGFR plays a critical role in cancer development and progression, including cell proliferation, apoptosis, angiogenesis, and metastatic spread. Mutations in this gene are associated with lung cancer. |
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