Anti-Human DR5/CD262 Rabbit Recombinant Antibody proteintech 98273-1-RR
$124.00
In stock
SKU
98273-1-RR
DR5, 242319H8, CD262, Death receptor 5, KILLER
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: tumor necrosis factor receptor superfamily, member 10b |
| Applications: FC | Observed Molecular Weight: BC001281 |
| Formulation: PBS, Azide | GenBank Accession Number: 8795 |
| Conjugate: Unconjugated | Gene Symbol: Unconjugated |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Liquid |
| Application: Flow Cytometry (FC) | RRID: Protein A purfication |
| Dilution: FC : 0.25 ug per 10^6 cells in a 100 ?l suspension | Conjugate: O14763 |
| Tested Reactivity: Human | Form: PBS with 0.09% sodium azide, pH 7.3. |
| Host / Isotype: Recombinant | Background Information: DR5, also known as CD262, TNFRSF10B, TRAILR2, TRICK2 and KILLER, is a widely expressed single-pass type I membrane protein belonging to the tumour necrosis factor receptor superfamily (TNFRSF). It is a receptor for TNF-related apoptosis-inducing ligand (TRAIL), which is a member of the tumor necrosis factor (TNF) family of cytokines and induces apoptosis in a wide variety of cells (PMID: 9311998). DR5 contains two extracellular cysteine-rich repeats, typical for TNF receptor (TNFR) family members, and a cytoplasmic death domain (DD), through which DR5 is capable to transmit the apoptotic signal (PMID: 9311998; 20531300). |
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