Anti-Human DDR1/CD167a Rabbit Recombinant Antibody proteintech 98200-1-RR

$124.00
In stock
SKU
98200-1-RR

 

DDR1, Cell adhesion kinase, CD167a, CD167 antigen-like family member A, CD167

Host / Isotype: Rabbit / IgG Class: Antibody
Reactivity: human Immunogen: discoidin domain receptor tyrosine kinase 1
 Applications: FC Observed Molecular Weight: NM_001297654
Formulation: PBS, Azide GenBank Accession Number: 780
Conjugate: Unconjugated Gene Symbol: AB_3672333
Tested Applications: Positive FC detected in Gene ID (NCBI): Unconjugated
Application: Flow Cytometry (FC) RRID: Liquid
Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension Conjugate: Protein A purfication
Tested Reactivity: Human Form: Q08345-1
Host / Isotype: Recombinant Background Information: DDR1, or CD167a, is a member of the receptor tyrosine kinase (RTK) family, which plays a significant role in various cellular processes including cell proliferation, adhesion, migration, and extracellular matrix (ECM) remodeling. DDR1 is known for its unique discoidin domain that allows it to bind specifically to certain collagens, initiating downstream signaling pathways that can lead to cell transformation and tumor progression. Abnormal activation of DDR1 is closely associated with the development of various solid tumors, and it has been shown that DDR1 can prevent immune cells from infiltrating triple-negative breast cancer (TNBC) and eliminate tumor cells.

 

 

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