CD109 Recombinant monoclonal antibody proteintech 85924-4-RR
$449.00
In stock
SKU
85924-4-RR
150 kDa TGF-beta-1-binding protein, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7, CD109 antigen, CD109 molecule, CPAMD7
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: CD109 molecule |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 180 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: CD109 |
| Conjugate: Unconjugated | Gene Symbol: 135228 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): Unconjugated |
| Application: Western Blot (WB) | RRID: Liquid |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Protein A purification |
| Tested Reactivity: Human | Form: Q6YHK3-1 |
| Host / Isotype: Recombinant | Background Information: CD109, also named as CPAMD7, is a member of the alpha2-macroglobulin/complement superfamily. It is a glycosylphosphatidylinositol (GPI)-linked cell surface glycoprotein of approximately 170kd which is found on the cell surface of platelets, activated T-cells, and endothelial cells. CD109 binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta). CD109 has been identified as part of the TGF-beta receptor system in human keratinocytes. Up regulation of CD109 expression has been observed in several different types of tumor.CD109 is a glycosyl-phosphatidylinositol-anchored glycoprotein that is a member of the a2-macroglobulin/C3, C4, C5 family of thioester-containing proteins. There're 2 forms of 150 (p150) and 120 kDa (p120) exist due to proteolytic degradation from a 180 kDa form. |
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