Anti-Human CEACAM1/3/6 (CD66a/c/d) Rabbit Recombinant Antibody proteintech 98061-1-RR
$84.00
In stock
SKU
98061-1-RR
CD66a/c/d, CD66c, CEACAM3, CEACAM6, CEACAM1
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| Applications: FC | Observed Molecular Weight: BC014473 |
| Formulation: PBS, Azide | GenBank Accession Number: 634 |
| Conjugate: Unconjugated | Gene Symbol: AB_3672208 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Unconjugated |
| Application: Flow Cytometry (FC) | RRID: Liquid |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Protein A purfication |
| Tested Reactivity: Human | Form: P13688 |
| Host / Isotype: Recombinant | Background Information: CEACAM1, also known as CD66a or BGP (biliary glycoprotein), is a member of the cacinoembryonic antigen (CEA) family which belongs to the immunoglobulin superfamily of cell adhesion molecules (PMID: 16919437). CEACAMs play major roles in cell-cell and cell-ECM adhesion and have been implicated in the control of cell proliferation, angiogenesis, and tissue remodeling (PMID: 23021083). CEACAM1 is a transmembrane glycoprotein that is expressed on epithelial, endothelial, and immune cells (PMID: 30314283). CEACAM1 has been demonstrated to play a role in morphogenesis, apoptosis, angiogenesis, cell proliferation, cell motility, fibrosis, and immunity (PMID: 31604530). This antibody is raised against 35-428 aa of human CEACAM1/CD66a and can cross-react with CEACAM6/CD66c and CEACAM3/CD66d. |
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