Anti-Human CD79a (HM57) Mouse IgG2a Recombinant Antibody proteintech 65610-1-MR
$69.00
In stock
SKU
65610-1-MR
B-cell antigen receptor complex-associated protein alpha chain, MB 1, MB 1 membrane glycoprotein, MB1, MB-1 membrane glycoprotein
| Host / Isotype: Mouse / IgG2a | Class: Antibody |
| Reactivity: human | Immunogen: CD79a molecule, immunoglobulin-associated alpha |
| Applications: FC (Intra) | Observed Molecular Weight: CD79A |
| Formulation: PBS, Azide | GenBank Accession Number: AB_3670357 |
| Conjugate: Unconjugated | Gene Symbol: Unconjugated |
| Tested Applications: Positive FC (Intra) detected in | Gene ID (NCBI): Liquid |
| Application: Flow Cytometry (FC) (INTRA) | RRID: Protein A purification |
| Dilution: FC (INTRA) : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: P11912 |
| Tested Reactivity: Human | Form: PBS with 0.09% sodium azide, pH 7.3. |
| Host / Isotype: Recombinant | Background Information: CD79a, also named as B-cell antigen receptor complex-associated protein alpha chain or MB-1 membrane glycoprotein, is a 226 amino acid protein, which contains one ITAM domain and one Ig-like C2-type (immunoglobulin-like) domain. CD79a is expressed in B cell and localizes in the cell membrane. CD79a is required in cooperation with CD79b for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79a is also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. |
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