Anti-Human CD3 (OKT3) Mouse IgG2a Recombinant Antibody proteintech 65569-1-MR
$59.00
In stock
SKU
65569-1-MR
CD3E, CD3 epsilon, CD3-epsilon, OKT3, T3E
| Host / Isotype: Mouse / IgG2a | Class: Antibody |
| Reactivity: human | Immunogen: CD3e molecule, epsilon (CD3-TCR complex) |
| Applications: FC | Observed Molecular Weight: BC049847 |
| Formulation: PBS, Azide | GenBank Accession Number: 916 |
| Conjugate: Unconjugated | Gene Symbol: ENSG00000198851 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): AB_3670323 |
| Application: Flow Cytometry (FC) | RRID: Unconjugated |
| Dilution: FC : 0.25 ug per 10^6 cells in a 100 ?l suspension | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: CD3 is a multimeric protein associated with the T-cell receptor (TCR) to form a complex involved in antigen recognition and signal transduction (PMID: 15885124). CD3 is composed of CD3γ, δ, ε, and ζ chains (PMID: 1826255). It is expressed by thymocytes in a developmentally regulated manner, T cells, and some NK cells (PMID: 3289580). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657). |
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