Anti-Human CD7 Rabbit Recombinant Antibody proteintech 98204-1-RR
$67.00
In stock
SKU
98204-1-RR
242402H8, CD7 molecule, GP40, LEU-9, T cell antigen CD7
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: CD7 molecule |
| Applications: FC | Observed Molecular Weight: NM_006137.7 |
| Formulation: PBS, Azide | GenBank Accession Number: 924 |
| Conjugate: Unconjugated | Gene Symbol: ENSG00000173762 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Unconjugated |
| Application: Flow Cytometry (FC) | RRID: Liquid |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Protein A purfication |
| Tested Reactivity: Human | Form: P09564 |
| Host / Isotype: Recombinant | Background Information: CD7, also known as Leu-9 or GP40, is a 40-kDa single-pass type I transmembrane glycoprotein belonging to the immunoglobulin superfamily. CD7 is expressed on thymocytes, T cells, NK cells, and cells in the early stages of T, B, and myeloid cell differentiation (PMID: 10530432). It is one of the earliest antigens to appear on cells of the T-lymphocyte lineage (PMID: 3501369). CD7 plays a significant role in T-cell and T-cell/B-cell interactions during early lymphoid development. It is involved in the regulation of cell signaling and biology, including T-cell activation, proliferation, and the expression of interleukin-2 receptor alpha (IL-2Rα) (PMID: 11485208). CD7 is not only a marker for T-cells but also has functional implications in immune cell interactions and adhesion. It can provide co-stimulatory signals and is associated with CD3 and CD45, participating in T-cell activation (PMID: 7523512). |
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