Anti-Human CD62L Rabbit Recombinant Antibody proteintech 98459-4-RR
$61.00
In stock
SKU
98459-4-RR
L-selectin, CD62 antigen-like family member L, gp90 MEL, gp90-MEL, hLHRc
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: selectin L |
| Applications: FC | Observed Molecular Weight: NM_000655.5 |
| Formulation: PBS, Azide | GenBank Accession Number: 6402 |
| Conjugate: Unconjugated | Gene Symbol: ENSG00000188404 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Unconjugated |
| Application: Flow Cytometry (FC) | RRID: Liquid |
| Dilution: FC : 0.25 ug per 10^6 cells in a 100 ?l suspension | Conjugate: Protein A purification |
| Tested Reactivity: Human | Form: P14151-1 |
| Host / Isotype: Recombinant | Background Information: CD62L, also known as L-selectin or SELL, is a member of the selectin family of adhesion molecules that also include CD62E (E-selectin) and CD62P (P-selectin) (PMID: 2663882, 2473156, 1382078). CD62L is a highly glycosylated protein of 95-105 kDa on neutrophils and 74 kDa on lymphocytes (PMID: 1382078; 1694883, 1695155). CD62L is expressed on the surface of most leukocytes, including lymphocytes, neutrophils, monocytes, eosinophils, hematopoietic progenitor cells, and immature thymocytes (PMID: 1694883, 1688580). It mediates the binding of lymphocytes to high endothelial venules (HEV) of peripheral lymph nodes through interactions with a constitutively expressed ligand, and is also involved in lymphocyte, neutrophil, and monocyte attachment to endothelium at sites of inflammation (PMID: 1382078). |
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