Anti-Human CD45RA (F8-11-13) Mouse IgG2a Recombinant Antibody proteintech 65590-1-MR
$59.00
In stock
SKU
65590-1-MR
CD45, EC:3.1.3.48, F8-11-13, GP180, L CA
| Host / Isotype: Mouse / IgG2a | Class: Antibody |
| Reactivity: human | Immunogen: protein tyrosine phosphatase, receptor type, C |
| Applications: FC | Observed Molecular Weight: BC014239 |
| Formulation: PBS, Azide | GenBank Accession Number: 5788 |
| Conjugate: Unconjugated | Gene Symbol: ENSG00000081237 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Unconjugated |
| Application: Flow Cytometry (FC) | RRID: Liquid |
| Dilution: FC : 0.25 ug per 10^6 cells in a 100 ?l suspension | Conjugate: Protein A purification |
| Tested Reactivity: Human | Form: P08575 |
| Host / Isotype: Recombinant | Background Information: CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097). CD45 exists as multiple isoforms due to alternative splicing of three exons (4, 5, and 6, designated A, B, and C) in the extracellular domain (PMID: 12414720). CD45RA is expressed on na?ve T cells, B cells, and monocytes (PMID: 1830500; 14687231). |
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