Anti-Human ICAM-1/CD54 (15.2) proteintech 65075-1-Ig
$67.00
In stock
SKU
65075-1-Ig
| Host / Isotype: Mouse / IgG1, kappa | Class: Antibody |
| Reactivity: human | Immunogen: intercellular adhesion molecule 1 |
| Applications: FC | Observed Molecular Weight: BC015969 |
| Formulation: PBS, Azide | GenBank Accession Number: 3383 |
| Conjugate: Unconjugated | Gene Symbol: ENSG00000090339 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): AB_2918379 |
| Application: Flow Cytometry (FC) | RRID: Unconjugated |
| Dilution: FC : 0.2 ug per 10^6 cells in 100 μl suspension | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Monoclonal | Background Information: ICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues (PMID: 19307690). ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin (PMID: 3086451; 9694714; 15979056). It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum (PMID: 2566624; 2538244; 2475784). |
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