Anti-Human CD31 (WM-59) Mouse IgG2a Recombinant Antibody proteintech 65614-1-MR
$61.00
In stock
SKU
65614-1-MR
EndoCAM, GPIIA, GPIIA', PECA1, PECAM 1
| Host / Isotype: Mouse / IgG2a | Class: Antibody |
| Reactivity: human | Immunogen: platelet/endothelial cell adhesion molecule |
| Applications: FC | Observed Molecular Weight: BC022512 |
| Formulation: PBS, Azide | GenBank Accession Number: 5175 |
| Conjugate: Unconjugated | Gene Symbol: ENSG00000261371 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): AB_3670361 |
| Application: Flow Cytometry (FC) | RRID: Unconjugated |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: CD31, also known as PECAM1 (Platelet endothelial cell adhesion molecule), is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. It is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, CD31 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489). |
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