METTL16 Polyclonal antibody proteintech 19924-1-AP
$449.00
In stock
SKU
19924-1-AP
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: human, rat, mouse | Immunogen: CatNo: Ag13889 Product name: Recombinant human METT10D protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-213 aa of BC001213 Sequence: MALSKSMHARNRYKDKPPDFAYLASKYPDFKQHVQINLNGRVSLNFKDPEAVRALTCTLLREDFGLSIDIPLERLIPTVPLRLNYIHWVEDLIGHQDSDKSTLRRGIDIGTGASCIYPLLGATLNGWYFLATEVDDMCFNYAKKNVEQNNLSDLIKVVKVPQKTLLMDALKEESEIIYDFCMCNPPFFANQLEAKGVNSRNPRRPPPSSVNTG Predict reactive species |
| Applications: WB, IHC, IF, ELISA | Observed Molecular Weight: 562 aa, 64 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC001213 |
| Conjugate: Unconjugated | Gene Symbol: METTL16 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 79066 |
| Application: Western Blot (WB) | RRID: AB_10639364 |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Rat, Mouse | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: Methyltransferase-like protein 16 (METTL16) is a human RNA methyltransferase that installs m6A marks on U6 small nuclear RNA (U6 snRNA) and S-adenosylmethionine (SAM) synthetase pre-mRNA. METTL16 is considered a protective gene, suppressing the development of OC, HCC, and endocrine system tumors (PMID: 33237039, PMID: 33133142, PMID: 34187307). However, the high expression of METTL16 has been linked with a poor survival rate in patients with breast cancer (PMID: 33362863). METTL16 has 2 isoforms with molecular weights of 64 and 26 kDa. |