CD86 Recombinant monoclonal antibody proteintech 83523-4-RR
$449.00
In stock
SKU
83523-4-RR
240429G12, Activation B7 2 antigen, Activation B7-2 antigen, B7 2, B70
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: CD86 molecule |
| Applications: WB, IF/ICC, ELISA | Observed Molecular Weight: 70 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: CD86 |
| Conjugate: Unconjugated | Gene Symbol: 942 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): ENSG00000114013 |
| Application: Western Blot (WB) | RRID: AB_3671150 |
| Dilution: WB : 1:1000-1:4000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Recombinant | Background Information: CD86 (also known as B7.2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. |
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