Anti-Human CD244 Rabbit Recombinant Antibody proteintech 98133-1-RR
$67.00
In stock
SKU
98133-1-RR
SLAMF4, NKR2B4, NK cell activation-inducing ligand, NAIL, h2B4
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: CD244 molecule, natural killer cell receptor 2B4 |
| Applications: FC | Observed Molecular Weight: BC053985 |
| Formulation: PBS, Azide | GenBank Accession Number: 51744 |
| Conjugate: Unconjugated | Gene Symbol: AB_3672279 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Unconjugated |
| Application: Flow Cytometry (FC) | RRID: Liquid |
| Dilution: FC : 5 ul per 10^6 cells in 100 μl suspension | Conjugate: Protein A purfication |
| Tested Reactivity: Human | Form: Q9BZW8 |
| Host / Isotype: Recombinant | Background Information: CD244, also known as SLAMF4 or 2B4, is a type I transmembrane glycoprotein belonging to the signaling lymphocyte activation molecule (SLAM) family. It consists of an extracellular segment with two immunoglobulin (Ig)-like domains, a transmembrane region, and a cytoplasmic domain containing tyrosine-based motifs (PMID: 9841922; 30546369). CD244 is present on natural killer (NK) cells, γδ T cells, a subset of CD8+ T cells, monocytes, basophils, dendritic cells, and myeloid-derived suppressor cells (MDSCs) (PMID: 30546369). It binds to CD48 with high affinity and transmits stimulatory or inhibitory signals that regulate immune function (PMID: 9841922; 18523281). |
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