Anti-Human CD15 Rabbit Recombinant Antibody proteintech 98616-1-RR
$61.00
In stock
SKU
98616-1-RR
Lewis X, SSEA-1
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: CD15 |
| Applications: IHC, FC | |
| Formulation: PBS, Azide | GenBank Accession Number: Liquid |
| Conjugate: Unconjugated | Gene Symbol: Protein A purification |
| Tested Applications: Positive IHC detected in | Gene ID (NCBI): PBS with 0.09% sodium azide, pH 7.3. |
| Application: Immunohistochemistry (IHC) | RRID: Store at 2 - 8°C. Stable for one year after shipment. |
| Dilution: IHC : 1:50-1:500 | |
| Tested Reactivity: Human | |
| Host / Isotype: Recombinant | Background Information: CD15, also known as stage-specific embryonic antigen-1 (SSEA-1) or Lewis X (LeX), is a cell surface glycan consisting of a trisaccharide with the structure Galβ1-4[Fucα1-3]GlcNAc (PMID: 18953356). CD15 is expressed on most terminally differentiated myeloid cells, including neutrophils, eosinophils, monocytes, macrophages, mast cells, and Langerhans cells. It has also been shown to be expressed on stem cells and progenitors in the embryonic and adult nervous system, Hodgkin's lymphoma cells, and cells from a variety of solid cancers (PMID: 19185848). CD15 acts as a ligand for selectins in transendothelial migration and is involved in phagocytosis and chemotaxis (PMID: 1362195). |
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