Anti-Human CD11b (ICRF44) Mouse IgG2a Recombinant Antibody proteintech 65582-1-MR
$59.00
In stock
SKU
65582-1-MR
ICRF44, CR3A, CR-3 alpha chain, CR 3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha
| Host / Isotype: Mouse / IgG2a | Class: Antibody |
| Reactivity: human | Immunogen: integrin, alpha M (complement component 3 receptor 3 subunit) |
| Applications: FC | Observed Molecular Weight: BC096346 |
| Formulation: PBS, Azide | GenBank Accession Number: 3684 |
| Conjugate: Unconjugated | Gene Symbol: ENSG00000169896 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): AB_3670334 |
| Application: Flow Cytometry (FC) | RRID: Unconjugated |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828). |
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