CIRBP Polyclonal antibody proteintech 10209-2-AP
$449.00
In stock
SKU
10209-2-AP
A18 hnRNP, A18HNRNP, CIRP
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human, Mouse, Rat And More (1) | Immunogen: CatNo: Ag0280 Product name: Recombinant human CIRBP protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-172 aa of BC000403 Sequence: MASDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAMNGKSVDGRQIRVDQAGKSSDNRSRGYRGGSAGGRGFFRGGRGRGRGFSRGGGDRGYGGNRFESRSGGYGGSRDYYSSRSQSGGYSDRSSGGSYRDSYDSYATHNE Predict reactive species |
| Applications: WB, IHC, IF/ICC, FC (Intra), IP, CoIP, RIP, ELISA | Observed Molecular Weight: 172 aa, 19 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC000403 |
| Conjugate: Unconjugated | Gene Symbol: CIRBP |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 1153 |
| Application: Western Blot (WB) | RRID: AB_2080263 |
| Dilution: WB : 1:2000-1:12000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: CIRBP, also named as A18HNRNP and CIRP, is a cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival[PMID: 19158277]. CIRBP is also involved in cap-independent translation upon moderate cold-shock. It acts as a translational activator. CIRBP is a suppressive rather stimulatory effect on proliferation[PMID: 19777567]. CIRBP can translocate from nucleus to cytoplasm under stresses such as UV irradation or heat shock. Suppression of CIRBP increased the apoptotic cell population of neural stem cells at moderate low temperature[PMID: 20735994]. This antibody (Catalog# 10209-2-AP) is a rabbit polyclonal antibody raised against the full-length CIRBP of human origin. |
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