SDHA Polyclonal antibody proteintech 14865-1-AP

$449.00
In stock
SKU
14865-1-AP

 

EC:1.3.5.1, FP, MC2DN1, PGL5, PPGL5

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: human, mouse, rat, pig, zebrafish Immunogen: CatNo: Ag6677 Product name: Recombinant human SDHA protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 336-664 aa of BC001380 Sequence: DLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIEESCRPGDKVPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQNHAAVFRVGSVLQEGCGKISKLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVRIDEYDYSKPIQGQQKKPFEEHWRKHTLSYVDVGTGKVTLEYRPVIDKTLNEADCATVPPAIRSY Predict reactive species
 Applications: WB, IHC, IF/ICC, IP, ELISA Observed Molecular Weight: 73 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC001380
Conjugate: Unconjugated Gene Symbol: SDHA
Tested Applications: Positive WB detected in Gene ID (NCBI): 6389
Application: Western Blot (WB) RRID: AB_11182164
Dilution: WB : 1:5000-1:50000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat, Pig, Zebrafish Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: SDHA, also named as SDH2, SDHF and Fp, belongs to the FAD-dependent oxidoreductase 2 family and FRD/SDH subfamily. SDHA is the flavoprotein subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). SDHA has 3 isoforms with the molecular mass of 73, 67 and 57 kDa, and the N-terminal (~5 kDa) can be removed in mature form. It can be detected a band of 68 kDa in cutaneous melanoma(PMID:21698147). SDHA may act as a tumor suppressor.

 

 

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