Angiogenin Recombinant monoclonal antibody proteintech 85635-1-RR
$449.00
In stock
SKU
85635-1-RR
ANG, ANG 1, ANG I, ANG1, ANGI
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: angiogenin, ribonuclease, RNase A family, 5 |
| Applications: WB, IF/ICC, ELISA | Observed Molecular Weight: 14 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: Angiogenin |
| Conjugate: Unconjugated | Gene Symbol: 283 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): Unconjugated |
| Application: Western Blot (WB) | RRID: Liquid |
| Dilution: WB : 1:1000-1:4000 | Conjugate: Protein A purification |
| Tested Reactivity: Human | Form: P03950 |
| Host / Isotype: Recombinant | Background Information: Angiogenin (ANG), an angiogenic ribonuclease, is a member of the vertebrate-specific, secreted RNASE superfamily. Angiogenin, originally identified as a tumor angiogenic factor, was related with the growth and metastasis of numerous tumors. Angiogenin has been proposed as a permissive factor for angiogenesis induced by other angiogenic factors, including vascular endothelial growth factor (VEGF), basic fibroblast growth factor, acidic fibroblast growth factor, and epidermal growth factor. Angiogenin production and secretion may be stimulated by hypoxia. Increased angiogenin serum levels have been associated with the incidence and severity of several human tumors, including HCC. It is a 17 kDa precursor which is cleaved to generate the 14 kDa mature protein. |