5 Lipoxygenase Recombinant monoclonal antibody proteintech 83794-4-RR
$449.00
In stock
SKU
83794-4-RR
ALOX5, 5-LO, 5LO, 5-lipoxygenase, 5 LOX
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: arachidonate 5-lipoxygenase |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 70-78 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: 5 Lipoxygenase |
| Conjugate: Unconjugated | Gene Symbol: 240 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671385 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:1000-1:4000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: ALOX5(arachidonate 5-lipoxygenase) is also named as LOG5, 5-LO and belongs to the lipoxygenase family. It catalyzes the first step in leukotriene biosynthesis, and plays a role in inflammatory processes. It is a 78 kDa iron-containing enzyme that translocates from the cytosol to associate with FLAP, and converts arachidonate in two steps into the unstable intermediate LTA4. It is essential for cysteinyl-leukotriene (cys-LT) production, critical mediators in asthma(PMID:12911785). |