5 Lipoxygenase Recombinant monoclonal antibody proteintech 83794-4-RR

$449.00
In stock
SKU
83794-4-RR

 

ALOX5, 5-LO, 5LO, 5-lipoxygenase, 5 LOX

Host / Isotype: Rabbit / IgG Class: Antibody
Reactivity: human Immunogen: arachidonate 5-lipoxygenase
 Applications: WB, IHC, ELISA Observed Molecular Weight: 70-78 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: 5 Lipoxygenase
Conjugate: Unconjugated Gene Symbol: 240
Tested Applications: Positive WB detected in Gene ID (NCBI): AB_3671385
Application: Western Blot (WB) RRID: Unconjugated
Dilution: WB : 1:1000-1:4000 Conjugate: Liquid
Tested Reactivity: Human Form: Protein A purfication
Host / Isotype: Recombinant Background Information: ALOX5(arachidonate 5-lipoxygenase) is also named as LOG5, 5-LO and belongs to the lipoxygenase family. It catalyzes the first step in leukotriene biosynthesis, and plays a role in inflammatory processes. It is a 78 kDa iron-containing enzyme that translocates from the cytosol to associate with FLAP, and converts arachidonate in two steps into the unstable intermediate LTA4. It is essential for cysteinyl-leukotriene (cys-LT) production, critical mediators in asthma(PMID:12911785).

 

 

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