Anti-Mouse CD31 (390) proteintech 65058-1-Ig
$45.00
In stock
SKU
65058-1-Ig
390, Pecam, PECAM 1, Pecam1, PECAM-1
| Host / Isotype: Rat / IgG2a, kappa | Class: Monoclonal |
| Reactivity: mouse | Immunogen: C3H/HeJ mouse hematopoietic progenitor cell line 32D Predict reactive species |
| Applications: IF/ICC, FC | Observed Molecular Weight: BC008519 |
| Formulation: PBS, Azide | GenBank Accession Number: 18613 |
| Conjugate: Unconjugated | Gene Symbol: AB_2918366 |
| Tested Applications: Positive IF/ICC detected in | Gene ID (NCBI): Unconjugated |
| Application: Immunofluorescence (IF)/ICC | RRID: Liquid |
| Dilution: IF/ICC : 1:50-1:500 | Conjugate: Affinity purification |
| Tested Reactivity: Mouse | Form: Q08481 |
| Host / Isotype: Rat / IgG2a, kappa | Background Information: Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489). |
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