Phospho-RASGRF1 (Ser927) Recombinant monoclonal antibody proteintech 82309-1-RR

$449.00
In stock
SKU
82309-1-RR

 

p RASGRF1, p RASGRF1 (Ser927), p RASGRF1 Ser927, Phospho RASGRF1, Phospho RASGRF1 (Ser927)

Host / Isotype: Rabbit / IgG Class: Recombinant
Reactivity: human Immunogen: Peptide Predict reactive species
 Applications: WB, ELISA Observed Molecular Weight: 134 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC040275
Conjugate: Unconjugated Gene Symbol: RASGRF1
Tested Applications: Positive WB detected in Gene ID (NCBI): 5923
Application: Western Blot (WB) RRID: AB_3085358
Dilution: WB : 1:1000-1:5000 Conjugate: Unconjugated
Tested Reactivity: Human Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: The RASGRF1 exchange factor, which is also known as CDC25 in Saccharomyces cerevisiae, promotes the exchange of Ras-bound GDP by GTP, is known to play central roles in pathways of cellular growth and differentiation. The serine residue at position 916 in mouse Ras-GRF1 is a PKA phosphorylation site, and the corresponding human residue is serine 927. It's reported that phosphorylation of serine 916 is necessary but not sufficient for maximal activation of mouse RASGRF1. The calculated MW of non-phosphorylated RASGRF1 is 145 kDa. 82309-1-RR can detect a band around 145 kDa, and can detect the increasing phosphorylation level after Forskolin treated.(PMID:15853814, 10601308)

 

 

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