Phospho-RASGRF1 (Ser927) Recombinant monoclonal antibody proteintech 82309-1-RR
$449.00
In stock
SKU
82309-1-RR
p RASGRF1, p RASGRF1 (Ser927), p RASGRF1 Ser927, Phospho RASGRF1, Phospho RASGRF1 (Ser927)
| Host / Isotype: Rabbit / IgG | Class: Recombinant |
| Reactivity: human | Immunogen: Peptide Predict reactive species |
| Applications: WB, ELISA | Observed Molecular Weight: 134 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC040275 |
| Conjugate: Unconjugated | Gene Symbol: RASGRF1 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 5923 |
| Application: Western Blot (WB) | RRID: AB_3085358 |
| Dilution: WB : 1:1000-1:5000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: The RASGRF1 exchange factor, which is also known as CDC25 in Saccharomyces cerevisiae, promotes the exchange of Ras-bound GDP by GTP, is known to play central roles in pathways of cellular growth and differentiation. The serine residue at position 916 in mouse Ras-GRF1 is a PKA phosphorylation site, and the corresponding human residue is serine 927. It's reported that phosphorylation of serine 916 is necessary but not sufficient for maximal activation of mouse RASGRF1. The calculated MW of non-phosphorylated RASGRF1 is 145 kDa. 82309-1-RR can detect a band around 145 kDa, and can detect the increasing phosphorylation level after Forskolin treated.(PMID:15853814, 10601308) |