Anti-Mouse CD86 Rabbit Recombinant Antibody proteintech 98025-1-RR

$63.00
In stock
SKU
98025-1-RR

 

B7-2, B70, B7.2, B7 2, B7

Host / Isotype: Rabbit / IgG Class: Recombinant
Reactivity: mouse Immunogen: Fusion Protein Predict reactive species
 Applications: FC Observed Molecular Weight: 35 kDa
Formulation: PBS, Azide GenBank Accession Number: Cd86
Conjugate: Unconjugated Gene Symbol: 12524
Tested Applications: Positive FC detected in Gene ID (NCBI): AB_3672169
Application: Flow Cytometry (FC) RRID: Unconjugated
Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension Conjugate: Liquid
Tested Reactivity: Mouse Form: Protein A purfication
Host / Isotype: Rabbit / IgG Background Information: CD86 (also known as B7-2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and CTLA-4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with CTLA-4 negatively regulates T-cell activation and diminishes the immune response. (PMID: 7513726; 1847722; 11029388; 27591335)

 

 

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