Anti-Mouse CD86 Rabbit Recombinant Antibody proteintech 98025-1-RR
$63.00
In stock
SKU
98025-1-RR
B7-2, B70, B7.2, B7 2, B7
| Host / Isotype: Rabbit / IgG | Class: Recombinant |
| Reactivity: mouse | Immunogen: Fusion Protein Predict reactive species |
| Applications: FC | Observed Molecular Weight: 35 kDa |
| Formulation: PBS, Azide | GenBank Accession Number: Cd86 |
| Conjugate: Unconjugated | Gene Symbol: 12524 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): AB_3672169 |
| Application: Flow Cytometry (FC) | RRID: Unconjugated |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Liquid |
| Tested Reactivity: Mouse | Form: Protein A purfication |
| Host / Isotype: Rabbit / IgG | Background Information: CD86 (also known as B7-2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and CTLA-4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with CTLA-4 negatively regulates T-cell activation and diminishes the immune response. (PMID: 7513726; 1847722; 11029388; 27591335) |