Anti-Human CD35 (E11) Mouse IgG2a Recombinant Antibody proteintech 65622-1-MR
$68.00
In stock
SKU
65622-1-MR
KN, E11, CR1, Complement receptor type 1, C3BR
| Host / Isotype: Mouse / IgG2a | Class: Recombinant |
| Reactivity: Human And More (1) | Immunogen: Human CD35 from Acute monocytic leukemia cells and normal blood monocytes Predict reactive species |
| Applications: FC | Observed Molecular Weight: 224 kDa |
| Formulation: PBS, Azide | GenBank Accession Number: CR1 |
| Conjugate: Unconjugated | Gene Symbol: 1378 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): ENSG00000203710 |
| Application: Flow Cytometry (FC) | RRID: AB_3670365 |
| Dilution: FC : 0.25 ug per 10^6 cells in 100 μl suspension | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Mouse / IgG2a | Background Information: CD35, also known as complement receptor type 1 (CR1) or C3b/C4b receptor, is a single-chain glycoprotein consisting of 30 repeating homologous protein domains known as short consensus repeats (~60 amino acids each) followed by transmembrane and cytoplasmic domains (PMID: 8765013). CD35 is variably expressed by granulocytes, monocytes, B cells, some T cells, erythrocytes, follicular dendritic cells, Langerhans cells, and glomerular podocytes (PMID: 19004497). CD35 acts as a receptor for C3b and C4b and plays important roles in the regulation of the complement cascade and clearance of immune complexes. |
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