KIM-1/HAVCR1 Recombinant monoclonal antibody proteintech 83221-2-RR
$449.00
In stock
SKU
83221-2-RR
HAVCR1, KIM-1, TIM-1, Kim1, KIM 1
| Host / Isotype: Rabbit / IgG | Class: Recombinant |
| Reactivity: mouse, rat | Immunogen: Recombinant protein Predict reactive species |
| Applications: WB, IF, ELISA | Observed Molecular Weight: 34 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NM_173149.2 |
| Conjugate: Unconjugated | Gene Symbol: Havcr1 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 286934 |
| Application: Western Blot (WB) | RRID: AB_3670906 |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Unconjugated |
| Tested Reactivity: Mouse, Rat | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: Kidney injury molecule 1 (KIM-1), also known as Hepatitis A virus cellular receptor 1 (HAVCR1), CD365, or T-cell immunoglobulin and mucin domain 1 (TIM-1), is a class I integral membrane glycoprotein, with an ectodomain containing Ig-like domain and a mucin domain. KIM-1 acts as a membrane receptor for hepatitis A virus (HAV) (PMID: 9658108; 8861957). KIM-1 provides a costimulatory signal for T cell activation and inhibits the development of peripheral tolerance (PMID: 16284246; 15793575). KIM-1 may be involved in the regulation of asthma and allergic diseases (PMID: 14534576). It has been reported that KIM-1 is shed into urine after acute kidney damage and is a marker of renal tubular injury (PMID: 14600030). |
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