TOP2B Recombinant monoclonal antibody proteintech 84049-1-RR
$449.00
In stock
SKU
84049-1-RR
240949F10, DNA topoisomerase 2-beta, EC:5.6.2.2, top2beta, TOPIIB
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: topoisomerase (DNA) II beta 180kDa |
| Applications: WB, IF/ICC, ELISA | Observed Molecular Weight: 180-190 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: TOP2B |
| Conjugate: Unconjugated | Gene Symbol: 7155 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671617 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: TOP2B belongs to the type II topoisomerase family. TOP2B control topological states of DNA by transient breakage and subsequent rejoining of DNA strands. TOP2B makes double-strand breaks. It is indirectly ivolved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene. |
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