SIK1 Recombinant monoclonal antibody proteintech 83897-4-RR
$449.00
In stock
SKU
83897-4-RR
240961H3, EC:2.7.11.1, MSK, salt inducible kinase 1, Salt-inducible kinase 1
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: salt-inducible kinase 1 |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: 85 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: SIK1 |
| Conjugate: Unconjugated | Gene Symbol: 150094 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671478 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: SIK1(Salt-inducible kinase 1) is also named SIK, SNF1LK, and belongs to the CAMK Ser/Thr protein kinase family. It associates constitutively with the NK regulatory complex and is responsible for increases in its catalytic activity following small elevations in intracellular sodium concentrations(PMID:17939993). SIK1 is required for the phosphorylation of class II HDACs and expression of MEF2 target genes in myocytes(PMID:17468767). Defects in SIK1 may be associated with some cancers, such as breast cancer. Loss of SIK1 correlates with poor patient outcomes in breast cancers(PMID:19622832). |
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