RAB1B Recombinant monoclonal antibody proteintech 83687-4-RR
$449.00
In stock
SKU
83687-4-RR
240635D9, EC:3.6.5.2, Ras related protein Rab 1B, Ras-related protein Rab-1B
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: RAB1B, member RAS oncogene family |
| Applications: WB, IHC, IF/ICC, FC (Intra), ELISA | Observed Molecular Weight: 22 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: RAB1B |
| Conjugate: Unconjugated | Gene Symbol: 81876 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671289 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: Ras-related protein Rab-1B (RAB1B) belongs to?the small GTPase superfamily and Rab family. Rab1b, a GTPase regulating secretory transport, was recently associated with targeting proteins to LDs in a Drosophila RNAi screen. Rab1b recruits lipid-synthesizing enzymes, facilitating Lipid droplets (LDs) growth. The small GTPase Rab1b interacts with diacylglycerol acyltransferase 2 to facilitate its targeting to the surface of lipid droplets. (PMID: 38809969). Rab1b, an extensively studied and established master regulator of ER-to-Golgi transport.?The mechanism of Rab1b's function is to promote ER to LD surface targeting of those triglyceride-synthesizing enzymes that can associate with the unique lipid monolayer comprising the LD surface (PMID: 38809969). Rab1b is a regulatory protein involved in both COPI and COPII transport?(PMID: 17429068). |
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