BBS4 Recombinant monoclonal antibody proteintech 82961-1-RR
$449.00
In stock
SKU
82961-1-RR
230303C2, Bardet Biedl syndrome 4, Bardet-Biedl syndrome 4 protein
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: Bardet-Biedl syndrome 4 |
| Applications: WB, IF/ICC, FC (Intra), ELISA | Observed Molecular Weight: 60 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BBS4 |
| Conjugate: Unconjugated | Gene Symbol: 585 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3670707 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: BBS4 (Bardet-Biedl syndrome protein 4) is one of the early BBS proteins discovered, with 35 mutations reported to cause the BBS phenotype (PMID: 26762677). BBS4 undergoes localization to the centriolar satellites of centrosomes and basal body of primary cilia, where it takes part in recruiting cargo to centriolar satellites and allowing the formation of a functional centrosomal microtubule organizing center (MTOC) (PMID: 25860617). Some research has found that BBS4 expression in humans during the development of CNS and sensory organs, concerning the cardinal clinical signs of BBS (PMID: 33860840). |
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