PSMD14/POH1 Recombinant monoclonal antibody proteintech 84767-3-RR
$449.00
In stock
SKU
84767-3-RR
PSMD14, 242160E7, 26S proteasome non-ATPase regulatory subunit 14, 26S proteasome-associated PAD1 homolog 1, EC:3.4.19.-
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse | Immunogen: proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: 33 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: PSMD14 |
| Conjugate: Unconjugated | Gene Symbol: 10213 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): Unconjugated |
| Application: Western Blot (WB) | RRID: Liquid |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Protein A purification |
| Tested Reactivity: Human, Mouse | Form: O00487 |
| Host / Isotype: Recombinant | Background Information: The PSMD14 (POH1, also known as Rpn11/MPR1/S13/CepP1) protein is a metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. PSMD14 is highly expressed in the heart and skeletal muscle. In carcinoma cell lines. down-regulation of PSMD14 by siRNA transfection had a considerable impact on cell viability causing cell arrest in the G0-G1 phase, ultimately leading to senescence. |
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