Osteoprotegerin/TNFRSF11B Recombinant monoclonal antibody proteintech 83506-1-RR
$449.00
In stock
SKU
83506-1-RR
TNFRSF11B, Osteoprotegerin, Osteoclastogenesis inhibitory factor, OPG, OCIF
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, rat | Immunogen: tumor necrosis factor receptor superfamily, member 11b |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 56 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: TNFRSF11B |
| Conjugate: Unconjugated | Gene Symbol: 4982 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671131 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human, Rat | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: Osteoprotegerin (OPG), also known as tumor necrosis factor receptor superfamily member 11B (TNFRSF11B) and osteoclastogenesis inhibitory factor (OCIF), belongs to the tumor necrosis factor (TNF) receptor superfamily. By binding to RANKL, OPG inhibits osteoclastic activity and promotes bone formation. OPG plays a key role in cell survival by inhibiting TRAIL-induced apoptosis. OPG also is involved in vascular biology, fibrosis, immunity, EMT, and the apoptosis of cancer cells (PMID: 35523775). |
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