NSD3 Recombinant monoclonal antibody proteintech 83116-2-RR
$449.00
In stock
SKU
83116-2-RR
WHSC1L1, DC28, EC:2.1.1.370, Histone-lysine N-methyltransferase NSD3, Nuclear SET domain-containing protein 3
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: Wolf-Hirschhorn syndrome candidate 1-like 1 |
| Applications: WB, IHC, IF/ICC, FC (Intra), ELISA | Observed Molecular Weight: 160-170 kDa, 68-72 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: WHSC1L1 |
| Conjugate: Unconjugated | Gene Symbol: 54904 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3670829 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: WHSC1L1, also named as NSD3 and DC28, belongs to the histone-lysine methyltransferase family and SET2 subfamily. It is histone methyltransferase. WHSC1L1 is a potently transforming oncogenes based on the number of altered phenotypes expressed by the cells. It contains a PWWP-domain that is a methyl-lysine recognition motif involved in histone code modification and epigenetic regulation of gene expression. Knockdown of WHSC1L1 in 8p11-12-amplified breast cancer cells resulted in profound loss of growth and survival of these cells. (PMID: 20940404). This antibody recognize the long isoform (160-170 kDa) and short isoform (68-72 kDa). |
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