PRDM16 Recombinant monoclonal antibody proteintech 83872-1-RR
$449.00
In stock
SKU
83872-1-RR
240662D3, EC:2.1.1.367, Histone-lysine N-methyltransferase PRDM16, KIAA1675, MDS1/EVI1 like gene 1
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: PR domain containing 16 |
| Applications: WB, IF/ICC, ELISA | Observed Molecular Weight: ~140 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: PRDM16 |
| Conjugate: Unconjugated | Gene Symbol: 63976 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671458 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: PR domain containing 16, also known as PRDM16, acts as a transcription coregulator that controls the development of brown adipocytes in brown adipose tissue. Previously, this coregulator was believed to be present only in brown adipose tissue, but more recent studies have shown that PRDM16 is highly expressed in subcutaneous white adipose tissue as well. The protein encoded by this gene is a zinc finger transcription factor. PRDM16 controls the cell fate between muscle and brown fat cells. Loss of PRDM16 from brown fat precursors causes a loss of brown fat characteristics and promotes muscle differentiation. |
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