Neurofibromin Recombinant monoclonal antibody proteintech 83620-5-RR
$449.00
In stock
SKU
83620-5-RR
NF1, 240540F2, neurofibromin 1, NF 1, NF-1
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: neurofibromin 1 |
| Applications: WB, FC (Intra), ELISA | Observed Molecular Weight: 250-280 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: Neurofibromin 1 |
| Conjugate: Unconjugated | Gene Symbol: 4763 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671233 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: NF1 codes for neurofibromin, a GTPase-activating protein that negatively regulates RAS/MAPK pathway activity by accelerating the hydrolysis of Ras-bound GTP. NF1 has a high mutation rate and mutations in NF1 can alter cellular growth control, and neural development, resulting in neurofibromatosis type 1 (NF1, also known as von Recklinghausen syndrome). |
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