MOSC2 Recombinant monoclonal antibody proteintech 83705-2-RR
$449.00
In stock
SKU
83705-2-RR
240747G6, EC:1.7.-.-, mARC2, Mitochondrial amidoxime reducing component 2, Moco sulfurase C-terminal domain-containing protein 2
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: MOCO sulphurase C-terminal domain containing 2 |
| Applications: WB, IHC, FC (Intra), ELISA | Observed Molecular Weight: 35-38 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: MOSC2 |
| Conjugate: Unconjugated | Gene Symbol: 54996 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671307 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: MOSC domain-containing protein 2 (also known as MOSC2), also known as MARC2, is a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability. Also, MOSC2 may be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis. The reductase activity is regulated under adipogenic conditions, and down-regulation of the terminal component MOSC2 resulted in decreased lipid synthesis, suggesting a possible physiological role of this enzyme system and its component MOSC2 in lipogenesis(PMID: 22203676). |
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