MFN2 Recombinant monoclonal antibody proteintech 82673-2-RR
$449.00
In stock
SKU
82673-2-RR
MARF, KIAA0214, HSG, EC:3.6.5.-, CPRP1
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, rat | Immunogen: mitofusin 2 |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: 86 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: MFN2 |
| Conjugate: Unconjugated | Gene Symbol: 9927 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): ENSG00000116688 |
| Application: Western Blot (WB) | RRID: AB_3086501 |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Rat | Form: Liquid |
| Host / Isotype: Recombinant | Background Information: Mitofusin-2 (MFN2), a?mitochondrial?membrane?protein, is a dynamin-like?GTPase?embedded in the outer mitochondrial membrane (OMM) which plays a central role in regulating?mitochondrial fusion?and cell metabolism (PMID:?35399520; 34026850). There are two human mitofusin isoforms MFN1 and MFN2,?MFN1 and MFN2 mediate outer membrane fusion,?OPA1?is involved in inner membrane fusion, and?DRP1?is responsible for mitochondrial fission (PMID:?17084350; 35399520). It has been shown that MFN2 participates in multiple cellular biological processes under physical and pathological conditions. Apart from mitochondria fusion, MFN2 is also involved in mitochondrial-ER contacts (MERCs), mitophagy, cellular apoptosis, and proliferation (PMID:?34026850). |
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
