CD79a Recombinant monoclonal antibody proteintech 84236-4-RR

$449.00
In stock
SKU
84236-4-RR

 

MB-1 membrane glycoprotein, MB1, MB 1 membrane glycoprotein, MB 1, B-cell antigen receptor complex-associated protein alpha chain

Host / Isotype: Rabbit / IgG Class: Antibody
Reactivity: human Immunogen: CD79a molecule, immunoglobulin-associated alpha
 Applications: WB, IHC, ELISA Observed Molecular Weight: 40-50 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: CD79A
Conjugate: Unconjugated Gene Symbol: 973
Tested Applications: Positive WB detected in Gene ID (NCBI): AB_3671789
Application: Western Blot (WB) RRID: Unconjugated
Dilution: WB : 1:5000-1:50000 Conjugate: Liquid
Tested Reactivity: Human Form: Protein A purfication
Host / Isotype: Recombinant Background Information: CD79a, also named as B-cell antigen receptor complex-associated protein alpha chain or MB-1 membrane glycoprotein, is a 226 amino acid protein, which contains one ITAM domain and one Ig-like C2-type (immunoglobulin-like) domain. CD79A is expressed in B cells and localizes in the cell membrane. CD79A is required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79A is also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells.

 

 

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