METTL1 Recombinant monoclonal antibody proteintech 84272-1-RR
$449.00
In stock
SKU
84272-1-RR
241108G8, C12orf1, EC:2.1.1.-, EC:2.1.1.33, methyltransferase like 1
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse | Immunogen: methyltransferase like 1 |
| Applications: WB, IF/ICC, FC (Intra), ELISA | Observed Molecular Weight: 31-35 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: METTL1 |
| Conjugate: Unconjugated | Gene Symbol: 4234 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671818 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: METTL1 methyltransferase mediates m7G methylation within miRNAs and regulates cell migration via its catalytic activity. METTL1 can be inactivated by phosphorylation at Ser27 by protein kinase B (PKBα). Overexpression of METTL1 is widely observed among human cancers. It is also crucial for the regulation of chemoresistance in cancer treatment. In addition, mutations in the human N7-methylguanosine (m7G) methyltransferase complex METTL1/WDR4 cause primordial dwarfism and brain malformation. |
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