SCN11A Recombinant monoclonal antibody proteintech 85740-1-RR
$449.00
In stock
SKU
85740-1-RR
hNaN, NaN, NAV1.9, PN5, SCN12A
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: sodium channel, voltage-gated, type XI, alpha subunit |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 205 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: SCN11A |
| Conjugate: Unconjugated | Gene Symbol: 11280 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): Unconjugated |
| Application: Western Blot (WB) | RRID: Liquid |
| Dilution: WB : 1:500-1:2000 | Conjugate: Protein A purification |
| Tested Reactivity: Human, Mouse, Rat | Form: Q9UI33 |
| Host / Isotype: Recombinant | Background Information: Sodium channel protein type 11 subunit alpha?(SCN11A, also known as Nav1.9) is crucial for generating action potentials and regulating neuronal excitability, particularly in nociceptive neurons of the dorsal root ganglia (DRG) and trigeminal ganglia (PMID: 33752606). Nav1.9 channels are involved in the formation of pain-sensing and have been implicated in peripheral inflammatory pain hypersensitivity. Additionally, SCN11A-mediated channels play a role in regulating colonic motility and neurotransmitter release in the enteric nervous system (PMID: 35711274). |
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