MDM1 Recombinant monoclonal antibody proteintech 83141-2-RR

$449.00
In stock
SKU
83141-2-RR

 

Nuclear protein MDM1, 230425E10

Host / Isotype: Rabbit / IgG Class: Antibody
Reactivity: human, mouse Immunogen: Mdm1 nuclear protein homolog (mouse)
 Applications: WB, IHC, ELISA Observed Molecular Weight: 102 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: MDM1
Conjugate: Unconjugated Gene Symbol: 56890
Tested Applications: Positive WB detected in Gene ID (NCBI): AB_3670841
Application: Western Blot (WB) RRID: Unconjugated
Dilution: WB : 1:5000-1:50000 Conjugate: Liquid
Tested Reactivity: Human, Mouse Form: Protein A purification
Host / Isotype: Recombinant Background Information: Mdm1 was upregulated during ciliogenesis in multiciliated tracheal epithelial cells and localized to centrioles and cilia when transfected into NIH/3T3 cells. Mdm1 is a microtubule-binding protein that inhibits centrosome duplication when overexpressed. Proteomic analysis revealed that Mdm1 was also detected in the mouse photoreceptor sensory cilium complex and the outer segment (OS) of photoreceptor cells in the retina, suggesting that Mdm1 might be involved in the regulation of the functions and structure of the centrosome, as well as cilia. (PMID: 36171205)

 

 

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