MDM1 Recombinant monoclonal antibody proteintech 83141-2-RR
$449.00
In stock
SKU
83141-2-RR
Nuclear protein MDM1, 230425E10
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse | Immunogen: Mdm1 nuclear protein homolog (mouse) |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 102 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: MDM1 |
| Conjugate: Unconjugated | Gene Symbol: 56890 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3670841 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: Mdm1 was upregulated during ciliogenesis in multiciliated tracheal epithelial cells and localized to centrioles and cilia when transfected into NIH/3T3 cells. Mdm1 is a microtubule-binding protein that inhibits centrosome duplication when overexpressed. Proteomic analysis revealed that Mdm1 was also detected in the mouse photoreceptor sensory cilium complex and the outer segment (OS) of photoreceptor cells in the retina, suggesting that Mdm1 might be involved in the regulation of the functions and structure of the centrosome, as well as cilia. (PMID: 36171205) |