MGP Monoclonal antibody proteintech 60055-1-Ig
$449.00
In stock
SKU
60055-1-Ig
GIG36, 1A1C3, Cell growth-inhibiting gene 36 protein, matrix Gla protein, MGLAP
| Host / Isotype: Mouse / IgG2a | Class: Monoclonal |
| Reactivity: human, mouse | Immunogen: CatNo: Ag1091 Product name: Recombinant human MGP protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-103 aa of BC005272 Sequence: MKSLILLAILAALAVVTLCYESHESMESYELNPFINRRNANTFISPQQRWRAKVQERIRERSKPVHELNREACDDYRLCERYAMVYGYNAAYNRYFRKRRGAK Predict reactive species |
| Applications: WB, IHC, IF/ICC, IF-P, IF-Fro, ELISA | Observed Molecular Weight: 103 aa, 13 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC005272 |
| Conjugate: Unconjugated | Gene Symbol: MGP |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 4256 |
| Application: Western Blot (WB) | RRID: AB_2143330 |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse | Form: Liquid |
| Host / Isotype: Mouse / IgG2a | Background Information: Matrix Gla protein (MGP) is is a vitamin K-dependent, extracellular matrix protein. MGP plays a pivotal role in preventing soft tissue calcification and local mineralization of the vascular wall. Vitamin K deficiency leads to inactive uncarboxylated MGP (ucMGP), which accumulates at sites of arterial calcification. However MGP is synthesized in many tissues and is especially enriched in embryonic tissues and in cancer cells. Defects in MGP are the cause of Keutel syndrome (KS), which is an autosomal recessive disorder characterized by abnormal cartilage calcification, peripheral pulmonary stenosis neural hearing loss and midfacial hypoplasia. |
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