MARS Recombinant monoclonal antibody proteintech 83690-5-RR
$449.00
In stock
SKU
83690-5-RR
MARS1, METRS, Methionyl-tRNA synthetase, Methionine--tRNA ligase, cytoplasmic, EC:6.1.1.10
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: methionyl-tRNA synthetase |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: 101 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: MARS |
| Conjugate: Unconjugated | Gene Symbol: 4141 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671294 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: The methionyl-tRNA synthetase (MARS) gene encodes cytoplasmic methionyl-tRNA synthetase (MetRS) responsible for catalyzing the ligation of methionine to tRNA. MetRS belongs to a family of aminoacyl-tRNA synthetases that play critical roles in protein biosynthesis by charging tRNAs with their cognate amino acids. MetRS overexpression was shown to be evident in human colon cancer patients. MetRS may thus be involved in oncogenic transformation. MetRS has been proven as a potential prognostic marker candidate for the clinical prognostic prediction of non-small-cell lung cancer (NSCLC) in patients. MetRS can also be used to detect intracellular oxidative stress and control protein synthesis under oxidative stress (PMID:?30271085, PMID: 34679529, PMID: 32404475). The calculated molecular weight of MetRS is 101 kDa. |
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