Kininogen 1 Recombinant monoclonal antibody proteintech 84175-5-RR
$449.00
In stock
SKU
84175-5-RR
KNG1, 241397C11, Alpha-2-thiol proteinase inhibitor, BDK, Bradykinin
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: kininogen 1 |
| Applications: WB, FC (Intra), ELISA | Observed Molecular Weight: 48 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: Kininogen 1 |
| Conjugate: Unconjugated | Gene Symbol: 3827 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671732 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: Kininogens are inhibitors of thiol proteases. Kininogen 1 plays important role in Kinin-kallikrein system. This KNG1 gene contains 10 exons and encodes two proteins through alternative splicing: high molecular weight kininogen (HMWK) (72kDa) and low molecular weight kininogen (LMWK) (48kDa) (PMID: 37442062). HMWK is produced by the liver together with prekallikrein. It acts mainly as a cofactor on coagulation and inflammation, and has no intrinsic catalytic activity. LMWK is produced locally by numerous tissues, and secreted together with tissue kallikrein. |
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