Anti-Mouse CD80 (16-10A1) proteintech 65076-1-Ig
$82.00
In stock
SKU
65076-1-Ig
B7 1, B7.1, Cd28l, CD80 antigen, Ly 53
| Host / Isotype: Armenian Hamster / IgG | Class: Monoclonal |
| Reactivity: mouse | Immunogen: CHO cell line transfected with mouse B7 (CD80) Predict reactive species |
| Applications: FC | Observed Molecular Weight: BC131959 |
| Formulation: PBS, Azide | GenBank Accession Number: 12519 |
| Conjugate: Unconjugated | Gene Symbol: AB_2918380 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Unconjugated |
| Application: Flow Cytometry (FC) | RRID: Liquid |
| Dilution: FC : 0.5 ug per 10^6 cells in 100 μl suspension | Conjugate: Affinity purification |
| Tested Reactivity: Mouse | Form: Q00609 |
| Host / Isotype: Armenian Hamster / IgG | Background Information: CD80 (also known as B7-1) is a type I membrane protein that is a member of the immunoglobulin superfamily, with an extracellular immunoglobulin constant-like domain and a variable-like domain required for receptor binding. It is expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, monocytes, and macrophages. CD80 is the receptor for the proteins CD28 and CTLA-4 found on the surface of T-cells. It is involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. CD80 also acts as a cellular attachment receptor for adenovirus subgroup B. (PMID: 7545666; 12015893; 16920215) |
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