IKZF4 Recombinant monoclonal antibody proteintech 83471-5-RR
$449.00
In stock
SKU
83471-5-RR
ZNFN1A4, Zinc finger protein Eos, KIAA1782, EOS, 240357D5
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: IKAROS family zinc finger 4 (Eos) |
| Applications: WB, IF/ICC, FC (Intra), ELISA | Observed Molecular Weight: BC160169 |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: 64375 |
| Conjugate: Unconjugated | Gene Symbol: AB_3671101 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): Unconjugated |
| Application: Western Blot (WB) | RRID: Liquid |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Protein A purfication |
| Tested Reactivity: Human | Form: Q9H2S9 |
| Host / Isotype: Recombinant | Background Information: IKZF4 is a member of the Ikaros family transcription factors. The Ikaros family was originally designated to function in hematopoiesis, but it is only recently that studies have begun to show the relevance of this family in T helper cell differentiation. IKZF3 was preferentially expressed in TH17 cells and governs TH17 differentiation by silencing IL-2 expression. By investigating the dynamics of the TH17 regulatory network, IKZF4 was proposed by Yosef et al. as a composite in the negative regulatory module for TH17. (PMID: 24644282) |
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