TMEM175 Recombinant monoclonal antibody proteintech 84554-1-RR
$449.00
In stock
SKU
84554-1-RR
241567B9, hTMEM175, Transmembrane protein 175
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: transmembrane protein 175 |
| Applications: WB, ELISA | Observed Molecular Weight: 56 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: TMEM175 |
| Conjugate: Unconjugated | Gene Symbol: 84286 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3672062 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:500-1:2000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: TMEM175 has two repeats of 6-transmembrane-spanning segments and has no GYG K+ channel sequence signature-containing, pore-forming P loop. Lysosomes lacking TMEM175 exhibit no K+conductance, have a markedly depolarized ΔΨ and little sensitivity to changes in [K+], and have compromised luminal pH stability and abnormal fusion with autophagosomes during autophagy. TMEM175 comprises a K+ channel that underlies the molecular mechanism of lysosomal K+ permeability. It has two isoforms with MW 41-45 kDa and 54-60 kDa. For optimal WB detection with this antibody, we recommend avoiding boiling the sample after lysis. |
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
