IFNAR1 Recombinant monoclonal antibody proteintech 83002-4-RR
$449.00
In stock
SKU
83002-4-RR
230549C8, AVP, CRF2 1, CRF2-1, Cytokine receptor class-II member 1
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human | Immunogen: interferon (alpha, beta and omega) receptor 1 |
| Applications: WB, FC, ELISA | Observed Molecular Weight: 80-140 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: IFNAR1 |
| Conjugate: Unconjugated | Gene Symbol: 3454 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3670748 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: Interferon alpha and beta receptor subunit 1 (IFNAR1) is a type I membrane protein that associates with IFNAR2 to form the receptor for type I interferons, including interferons-alpha, -beta, and -lambda. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2, and then increase transcription of the IFN-induced genes whose products exert antiviral, immunomodulatory, and antiproliferative effects. |