ICAM-1/CD54 Recombinant monoclonal antibody proteintech 83696-3-RR

$449.00
In stock
SKU
83696-3-RR

 

CD54, ICAM-1, ICAM-12, Icam1, 240725C2

Host / Isotype: Rabbit / IgG Class: Antibody
Reactivity: rat Immunogen: intercellular adhesion molecule 1
 Applications: WB, IHC, IF-P, ELISA Observed Molecular Weight: 85 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: Icam1
Conjugate: Unconjugated Gene Symbol: 25464
Tested Applications: Positive WB detected in Gene ID (NCBI): AB_3671299
Application: Western Blot (WB) RRID: Unconjugated
Dilution: WB : 1:5000-1:50000 Conjugate: Liquid
Tested Reactivity: Rat Form: Protein A purification
Host / Isotype: Recombinant Background Information: ICAM-1 (CD54) is a transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues (PMID: 19307690). ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin (PMID: 3086451; 9694714; 15979056). It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum (PMID: 2566624; 2538244; 2475784).

 

 

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