HER2/ErbB2 Recombinant monoclonal antibody proteintech 84128-5-RR
$449.00
In stock
SKU
84128-5-RR
Her2 / ErbB2, Her2, Erbb2, EC:2.7.10.1, CD340
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: mouse | Immunogen: v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) |
| Applications: WB, IF/ICC, ELISA | Observed Molecular Weight: 185 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: Erbb2 |
| Conjugate: Unconjugated | Gene Symbol: 13866 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3671687 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:1000-1:6000 | Conjugate: Liquid |
| Tested Reactivity: Mouse | Form: Protein A purfication |
| Host / Isotype: Recombinant | Background Information: Her2, or ErbB2, is a member of the EGF receptor family of receptor tyrosine kinases. It has no ligand-binding domain of its own. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signaling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. |
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